Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana
Status:
Active, not recruiting
Trial end date:
2022-03-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess the early longitudinal metabolic effects including
insulin sensitivity in HIV-exposed uninfected (HEU) children compared to HIV-unexposed
uninfected (HUU) children; as well as to determine differences in the effects of neonatal
zidovudine (AZT) vs. nevirapine (NVP) prophylaxis on early longitudinal changes in insulin
sensitivity in the first 3 years of life.
Phase:
Phase 4
Details
Lead Sponsor:
Ann & Robert H Lurie Children's Hospital of Chicago
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)