Overview

Study of H2 Antagonist and a Proton Pump Inhibitor of Selpercatinib in Healthy Participants

Status:
Completed
Trial end date:
2019-09-03
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to learn about how H2 antagonist (ranitidine) and proton pump inhibitor (PPI) (omeprazole) affect Selpercatinib in healthy participants. Information about safety and tolerability will be collected. The study will last up to about 9 weeks, inclusive of screening period.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Eli Lilly and Company
Collaborator:
Loxo Oncology, Inc.
Treatments:
Omeprazole
Ranitidine
Ranitidine bismuth citrate