Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS
Status:
Completed
Trial end date:
1996-08-01
Target enrollment:
Participant gender:
Summary
To compare the safety and efficacy of two doses of clarithromycin in combination with
ethambutol and either rifabutin or clofazimine for the treatment of disseminated
Mycobacterium avium Complex (MAC) disease in AIDS patients.
Recommendations have been issued for AIDS patients with disseminated MAC to be treated with
at least two antimycobacterial agents and for every regimen to include a macrolide
(clarithromycin or azithromycin). However, the optimal treatment for disseminated MAC remains
unknown.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)