Study of Fluconazole in Children With Autism Spectrum Disorder
Status:
Unknown status
Trial end date:
2011-07-01
Target enrollment:
Participant gender:
Summary
Antifungal therapy is widely used for individuals with Autism Spectrum Disorders (ASD). The
current investigation will examine the effects of fluconazole on behavioral functioning among
children with ASD. This is a double-blind, randomized, placebo-controlled study of oral
fluconazole in children who meet criteria for ASD. Pre- and post-treatment behavioral ratings
will be used to evaluate the efficacy of fluconazole therapy. In addition, children will
undergo comprehensive medical history, physical examination, and laboratory analyses.
Our objective is to quantify differences in behavioral functioning between the fluconazole
treatment and a placebo. Our primary hypothesis is that, on average and relative to the
placebo, children with ASD who receive fluconazole will show greater improvements in symptoms
of autism.
Phase:
N/A
Details
Lead Sponsor:
The Center for Autism and Related Disorders
Collaborators:
The International Child Development Resource Center Thoughtful House