Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia
Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
In this study, Erlotinib and 5-Fluorouracil (5-FU), Leucovorin and Oxaliplatin (a regimen
known also as FOLFOX-6) will be the chemotherapy study drugs. The main purpose of this study
is to test the safety and effectiveness of this combination of chemotherapy drugs and to see
how they affect your cancer.
Another purpose of this study is to examine samples from your blood and tumor. This research
will be done to better understand how subjects respond to treatment. Specifically,
researchers will look at the way your genes and proteins respond to drugs like those used in
this study.
Phase:
Phase 2
Details
Lead Sponsor:
Translational Oncology Research International
Collaborators:
OSI Pharmaceuticals Sanofi University of California, Los Angeles