Study of Effects of Sildenafil on Patients With Fontan Heart Circulation
Status:
Unknown status
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
The study will investigate the cardiovascular effects of sildenafil on patients with Fontan
circulation. Recent studies suggest that sildenafil may improve exercise in patients with
Fontan circulation. However, why this occurs is not known. The study will used specialized
catheters to measure pressure and volume. The measure of pressure and volume leads to more
detailed analysis of heart function. Patients will receive either sugar pill or sildenafil
prior to catheterization. It is believed that sildenafil will improve relaxation and
contraction of the heart.