Overview Study of Cryoablation and Nirogacestat for Desmoid Tumor Status: RECRUITING Trial end date: 2028-02-01 Target enrollment: Participant gender: Summary The primary purpose of this protocol is Systemic therapy with oral study agent, nirogacestat, followed by a single cryoablation procedure.Phase: PHASE2 Details Lead Sponsor: Nam BuiCollaborator: SpringWorks Therapeutics, Inc.Treatments: Cryosurgerynirogacestat