Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment.

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether colchicine is safe and effective in treatment and prevention of recurrent pericarditis after failure of conventional treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Azienda Sanitaria Locale 3, Torino
• Treatments: Colchicine

Criteria

Inclusion Criteria:

• Patients with the second and subsequent attack of recurrent pericarditis,

• Age≥ 18 years,

• Informed consent.

Exclusion Criteria:

• Suspected neoplastic, tuberculous, or purulent etiology,

• Known severe liver disease and/or elevated transaminases >1.5 times the upper limit of normality,

• serum creatinine>2.5 mg/dl,

• Serum CK over the upper limit of normality or Known myopathy,

• Known gastrointestinal or blood disease,

• Pregnant or lactating women or women not protected by a contraception method,

• Known hypersensibility to colchicine,

• Treatment with colchicine at the enrolment.