Overview

Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences

Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of the study is to determine whether colchicine is safe and effective in the treatment of acute pericarditis and the prevention of subsequent recurrences.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Azienda Sanitaria Locale 3, Torino
Treatments:
Colchicine
Criteria
Inclusion Criteria:

- Patients with acute pericarditis (index attack)

- Ageā‰„ 18 years

- Informed consent

Exclusion Criteria:

- Suspected neoplastic, tuberculous, or purulent etiology

- Known severe liver disease and/or elevated transaminases >1.5 times the upper limit of
normality

- Serum creatinine >2.5 mg/dl

- Serum creatine kinase (CK) over the upper limit of normality or known myopathy

- Known gastrointestinal or blood disease

- Pregnant or lactating women or women not protected by a contraception method

- Known hypersensibility to colchicine

- Treatment with colchicine at enrolment