Study of Clozapine for the Treatment of Psychosis in Patients With Idiopathic Parkinson's Disease
Status:
Completed
Trial end date:
1997-11-01
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Determine the efficacy and tolerability of clozapine in ameliorating psychosis
in patients with idiopathic Parkinson's disease (PD).
II. Determine the adverse effects of clozapine on motor function in this patient population.
III. Determine the safety of clozapine in psychotic PD patients taking multiple anti-PD
medications.
IV. Describe the phenomenology of drug induced psychosis in PD.