Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this treatment research study is to assess the effectiveness of buprenorphine maintenance treatment for opioid dependence delivered in a primary care clinic setting. This study will determine whether buprenorphine treatment in primary care is effective in reducing cravings, reducing illicit opioid use, reducing addiction severity, and retaining patients in primary care treatment for opioid dependence.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York State Psychiatric Institute
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Analgesics, Opioid; Buprenorphine

Criteria

Inclusion Criteria:

• DSM-IV criteria for current opioid dependence

• Must be seeking treatment

• Must describe opioid medication or heroin as primary drug of abuse

• Must be financially able to receive treatment at the primary care clinic site and to receive medication (e.g., Medicaid)

• Able to give informed consent and comply with study procedures

Exclusion Criteria:

• Axis I psychiatric disorder(s) as defined by DSM-IV-TR that are unstable or would be disrupted by study participation

• Individuals at significant risk for suicide based on current mental state

• DSM-IV dependence with physiologic dependence other than opioid and nicotine

• Women must not be pregnant or lactating, and must agree to use a proven effective method of contraception and not become pregnant during the study

• Unstable physical disorder that might make participation hazardous

• Known allergy, sensitivity or adverse reaction to buprenorphine

• Current buprenorphine maintenance

• Inability to read or understand the self-report assessment forms unaided