Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether adding nebulized inhaled steroids to the standard care of acutely ill ED patients with refractory acute asthma helps improve forced expiratory volume at one second (FEV1) and decrease the need for hospitalization.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwell Health
• Collaborators: AstraZeneca; Jacobi Medical Center; Nassau University Medical Center
• Treatments: Albuterol; Bromides; Budesonide; Ipratropium; Prednisone

Criteria

Inclusion Criteria:

• FEV1<50% predicted after bronchodilator therapy, age 18-60, presenting to an emergency department with acute asthma

Exclusion Criteria:

• other chronic lung disease, >15 pack years smoking