Study of Blood Lactate Levels in Patients Treated With Antipsychotics

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

Blood lactate levels in patients receiving typical or atypical antipsychotics have not been described in the literature.

The goal of this study is to assess the dynamics of lactate levels in the blood from typical or atypical antipsychotics not confounded by prior antipsychotic treatments, the investigators conducted a prospective study of lactate levels in patients receiving antipsychotic medication. The investigators hypothesized that 6 months of treatment with haloperidol or olanzapine would result in a change in blood lactate levels and extrapyramidal side effects.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital of Split; University of Split
• Treatments: Antipsychotic Agents; Haloperidol; Haloperidol decanoate; Olanzapine

Criteria

Inclusion Criteria:

• Men aged 20 - 50 years

• Not taking any antipsychotic medication 1 month prior to the study

• Diagnosed psychotic disorder

Exclusion Criteria:

• Female

• Tobacco use

• Diabetes mellitus

• Baseline lactate blood level over 2.0 mmol/L