Study of BLZ-100 in Pediatric Subjects With CNS Tumors
Status:
Completed
Trial end date:
2018-08-01
Target enrollment:
Participant gender:
Summary
Many types of cancer are primarily treated with surgery and patient survival is directly
related to the extent to which the tumor is able to be removed. It is often difficult for
surgeons to distinguish tumor tissue from normal tissue or to detect tumor cells that have
spread from the original tumor site, resulting in incomplete removal of the tumor and reduced
patient survival. In some sites, such as the brain, it is critical to avoid damage to normal
tissue around the tumor to prevent adverse effects of surgery on function. The investigators
hypothesize that BLZ-100 will improve surgical outcomes by allowing surgeons to visualize the
edges of the tumor and small groups of cancer cells that have spread to other sites in
real-time as they operate. This is a safety study to assess the safety of BLZ-100 in
pediatric patients with central nervous system tumors.