Study of Avastin (Bevacizumab) to Reverse Acquired Estrogen Independence in Previously Hormone Responsive Metastatic Breast Ca.

• Status: Completed
• Trial end date: 2011-04-01

Summary

The purpose of this study is to determine if acquired hormone therapy resistance can be reversed by Avastin (Bevacizumab), as measured by time to disease progression and evaluate toxicity of the combination of hormone treatment plus Avastin (Bevacizumab).

• Phase: Phase 2

Details

• Lead Sponsor: University of Alabama at Birmingham
• Collaborator: Genentech, Inc.
• Treatments: Anastrozole; Bevacizumab; Estrogens; Exemestane; Letrozole; Tamoxifen