Study of Antenatal Thyrotropin-Releasing Hormone in Women in Premature Labor to Prevent Lung Disease in Preterm Infants

• Status: Completed
• Trial end date: 1998-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

OBJECTIVES:

I. Assess the efficacy and safety of antenatal administration of thyrotropin-releasing hormone to women in premature labor to improve pulmonary outcomes in preterm infants.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Collaborator: Children's Hospital of Philadelphia
• Treatments: Calcitonin; Hormones; Thyrotropin-Releasing Hormone

Criteria

• Pregnant women in active labor with 24-29 weeks gestation

• Not eligible if any of the following is present: Bleeding Infection Hypertension (greater than 140/90 mmHg) Fetus with hydrops or life-threatening anomalies One dead fetus in multiple pregnancy