Overview

Study of ACY-1215 Alone and in Combination With Bortezomib and Dexamethasone in Multiple Myeloma

Status:
Completed
Trial end date:
2016-12-03
Target enrollment:
Participant gender:
Summary
Phase 1(a & b): To evaluate the side effects and determine the best dose of oral ACY-1215 as monotherapy, and also in combination with bortezomib and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma. Phase 2a: To determine the objective response rate of oral ACY-1215 in combination with bortezomib and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Acetylon Pharmaceuticals Incorporated
Celgene
Collaborator:
The Leukemia and Lymphoma Society
Treatments:
BB 1101
Bortezomib
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Ricolinostat