Overview

Study in Asia of the Combination of TACE With Sorafenib in HCC Patients

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
TACE possibly plays a significant role in contributing to a subgroup of surviving residual tumor tissue which is characterized by more aggressive biology. This explains the strong scientific rationale for exploring the role of anti-angiogenic therapy such as sorafenib to remedy and strengthen the therapeutic efficacy of TACE to combat liver cancers. Sorafenib plays a prominent auxiliary role by further suppressing the tumor growth and prolonging the time to recurrence and progression. Performing TACE under sorafenib administration may have synergic effect on hepatic tumoral lesions.
Phase:
Phase 2
Details
Lead Sponsor:
Taipei Veterans General Hospital, Taiwan
Treatments:
Doxorubicin
Liposomal doxorubicin
Sorafenib