Study for Optimizing Anti-inflammatory Prophylaxis
Status:
Completed
Trial end date:
2019-12-18
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate which anti-inflammatory treatment is best at
preventing postoperative inflammation following cataract surgery. We want to compare topical
prophylaxis with NSAID eye drops to topical prophylaxis with a combination of NSAID and
prednisolone. We also want to compare topical prophylaxis with eye drops to drop-less surgery
where the anti-inflammatory drug is administered to the subtenonal space at the conclusion of
the surgical procedure. In addition, we want to investigate if topical anti-inflammatory
prophylaxis should be initiated preoperatively or postoperatively. The primary outcome is
change in central macular thickness, measured by optical coherence tomography, 3 months after
surgery.