Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
The objectives of the trial are:
To assess safety, tolerability and activity of nelfinavir given neo-adjuvant and concomitant
to chemoradiotherapy with temozolomide in patients with a newly diagnosed glioblastoma
multiforme.
To describe the possible effect of nelfinavir on functional imaging To describe the activity
of nelfinavir in vivo on blocking the AKT pathway.