Study With Modafinil in Patients Treated With Docetaxel-Based Chemotherapy for Metastatic Breast or Prostate Cancer (MOTIF)
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
The primary objective is:
- To determine the efficacy of modafinil in the reduction of fatigue in patients with
metastatic breast or prostate cancer undergoing docetaxel-based chemotherapy
The secondary objectives are:
- To determine the effect of modafinil on quality of life (QoL) during docetaxel-based
chemotherapy
- To determine the effect of modafinil on patients physical activity level, functional
status, number of chemotherapy cycles tolerated, sleep disturbance and depression,
during docetaxel-based chemotherapy
- To investigate the impact of tumour type, patient physical activity level, functional
status, sleep disturbance and depression on the efficacy of modafinil at improving
fatigue and quality of life during docetaxel-based chemotherapy.
- To determine the safety and tolerability of modafinil during docetaxel-based
chemotherapy