Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
To investigate the effect of acid reducing agents (an antacid and an H2-receptor antagonist
and a proton pump inhibitor) on palbociclib bioavailability in the presence of food.
Phase:
Phase 1
Details
Lead Sponsor:
Pfizer
Treatments:
Aluminum Hydroxide Aluminum hydroxide, magnesium hydroxide, simethicone drug combination Antacids Anti-Ulcer Agents Famotidine Magnesium Hydroxide Palbociclib Rabeprazole TEMPO