Study Of Single Doses Of PF-06291826 (Tafamidis) In Japanese And Western Subjects
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is the following:
- To evaluate the safety, tolerability, and pharmacokinetics (PK) of orally administered
tafamidis in Japanese and Western healthy volunteers at single dose.
- To compare Japanese and Western PK profiles.
- Determine the PD stabilization effect of tafamidis on human transthyretin (TTR) in a
validated ex vivo assay.