Study Examing The Effect Of Omeprazole On Safety, Tolerability And How The Body Processes An Experimental Drug
Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
Experiment in the test tube indicated that CP-945,598 becomes less soluble with increase of
pH (less acidity). Changes in stomach acid levels may affect the solubility of CP-945,598,
therefore, alters its availability in the blood. Omeprazole decreases acid levels in stomach.
This study will compare the time course of drug concentrations in the body, safety, and
tolerability of CP-945,598 given with and without omeprazole.