Overview
Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy
Status:
Completed
Completed
Trial end date:
2007-02-01
2007-02-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study is to evaluate the safety and tolerbility of ascending multiple oral doses of AGG-523 in healthy subjects and in subjects with osteoarthritis.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Wyeth is now a wholly owned subsidiary of Pfizer
Criteria
Inclusion Criteria:- Healthy men or women, aged 18 to 40 years and subjects with osteoarthritis of the
knee, aged 40 to 75 years.
- Women must be of non-childbearing potential, defined as surgically sterile with
documentation of ultrasound.
- Must be nonsmoker or smoke less than 10 cigarettes per day.