Study Evaluating the Efficacy of Nifedipine GITS - Telmisartan Combination in Blood Pressure Control.
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
Patients having uncontrolled or poorly controlled hypertension are at risk of experiencing
cardiovascular events such as myocardial infarction or stroke. To reduce this risk an
appropriate antihypertensive therapy should allow to reach a target blood pressure of less
than 130/80 mmHg in order to maximise cardiovascular protection.The purpose of this study is
to evaluate the efficacy in blood pressure control when anti-hypertensive therapy is
initiated with a combination of low dose Nifedipine GITS and Telmisartan compared to a
regimen starting with monotherapy before adding the other drug.The primary efficacy parameter
will be the 24 hour mean systolic Blood Pressure on Ambulatory Blood Pressure Monitoring
(ABPM) at 16 weeks of treatment compared to baseline