Study Evaluating of Calcineurin Inhibitors Versus Sirolimus in Renal Allograft Recipient
Status:
Terminated
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
This study will evaluate whether conversion from cyclosporine, a calcineurin inhibitor (CI)
to sirolimus (SRL) results in improved long-term renal function without a negative impact on
safety or immunosuppressive efficacy, and to further examine the potential of SRL to reduce
the severity and/or progression of chronic allograft nephropathy (CAN).