Overview

Study Evaluating Effect of Esomeprazole, Omeprazole or Lansoprazole on the Pharmacodynamics (PD) and Pharmacokinetics (PK) of Clopidogrel

Status:
Completed

Trial end date:
2011-05-01

Target enrollment:

Participant gender:

Summary

The aim of this study is to determine if there is a pharmacological interaction between clopidogrel and different types of proton pump inhibitors (PPIs), and if the extent of this possible interaction would change over time.

Phase:

Phase 1

Details

Lead Sponsor:

AstraZeneca

Treatments:

Clopidogrel
Dexlansoprazole
Esomeprazole
Lansoprazole
Omeprazole
Ticlopidine