Overview

Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients

Status:
Completed

Trial end date:
2020-10-13

Target enrollment:

Participant gender:

Summary

This study is to compare the efficacy and safety of defibrotide prophylaxis in addition to best supportive care versus best supportive care alone in the prevention of hepatic veno- occlusive disease (VOD) in adult and pediatric patients undergoing hematopoietic stem cell transplant who are at high risk or very high risk of developing VOD.

Phase:

Phase 3

Details

Lead Sponsor:

Jazz Pharmaceuticals

Treatments:

Defibrotide