Overview

Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial

Status:
Completed
Trial end date:
2018-11-19
Target enrollment:
Participant gender:
Summary
The Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial is a multicenter, randomized, controlled clinical trial of 1400 patients that will include approximately 60 enrolling sites. The study hypotheses are that treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL - 130 mg/dL) will be safe and result in improved 3 month outcome after stroke.
Phase:
Phase 3
Details
Lead Sponsor:
University of Virginia
Collaborators:
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS)
Neurological Emergencies Treatment Trials Network (NETT)
Treatments:
Benzocaine
Insulin
Insulin, Globin Zinc