Stopping Benzodiazepines and Related Molecules Among Elderly Living in Residential Institutions
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Intervention randomized controlled open study with 2 parallel arms . The objective of this
study is to evaluate the feasibility of stopping the benzodiazepines treatment in elderly
living in nursing homes.
It will check that the judgment of these molecules has no pejorative effect on sleep or
behavior of residents and does not induce withdrawal syndrome. Two patient groups will be
constituted. One will begin a gradual withdrawal of benzodiazepines in six weeks. The other
group will continue his treatment and withdrawal will be proposed after 8 weeks by his
general practitioner (delayed intervention).
Effects on sleep will be assessed by wrist actimetry for 10 weeks and a sleep diary . The
repercussions of withdrawal on behavior will be rated by the NPI scale.