Stopping Antihypertensive Treatment amOng Hypertensive Patients in Primary Care (STOP-Trial)
Status:
Completed
Trial end date:
2020-10-21
Target enrollment:
Participant gender:
Summary
The STOP-Trial is a prospective multicenter nonrandomized open study on grade I hypertension,
performed by General practitioners.
The study will be conducted in parallel in the Clinical Investigation Center Plurithematic
(CIC-P)1433 of Nancy (the study coordinating center) by the general practitioners
investigators of the CIC-P.
The main purpose of the study is to determine the factors associated with the rate of
patients remaining normotensive one year after stopping their antihypertensive monotherapy or
low dose dual therapy:
- white coat hypertension
- primary diagnosis by home blood pressure measurements (HBPM) /ambulatory blood pressure
measurements (ABPM) /clinical measure
- initial blood pressure level
- compliance
- therapeutic class versus others
- age
- gender
- weight variation
- modification of lifestyle
- concomitant treatments and associated substances
- ...
The primary endpoint will be the rate of normotensive patients at one year (i.e. HBPM values
<135/85 mmHg).