Steroids in the Maintenance of Remission of Proliferative Lupus Nephritis
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
There is debate as to whether long-term low-dose steroids such as prednisolone help to
suppress relapses of systemic lupus erythematosus (SLE) in patients who are in remission from
their lupus nephritis. If low-dose prednisolone reduces relapses, these beneficial effects
may be counter-balanced by the long-term side-effects associated with prednisolone. This
pilot study will determine the feasibility of conducting a larger randomized control trial
that will answer the question of whether or not long-term low-dose prednisolone (5 - 7.5
mg/day) reduces the flares of SLE in patients with previous lupus nephritis.
Phase:
Phase 3
Details
Lead Sponsor:
Cambridge University Hospitals NHS Foundation Trust