Steroids in Fulminant Hepatitis A in the Pediatric Age Group
Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
Fulminant hepatic failure (FHF) in children is a potentially devastating disease. The
mortality rate may reach 80-90% in the absence of liver transplantation. Liver injury is
considered to be mainly immune mediated with augmentation of cytolytic pathways of infected
hepatocytes. For that, it is suggested that corticosteroids modulate the activity of the
disease by suppressing the immune system.
Phase:
Phase 4
Details
Lead Sponsor:
National Liver Institute, Egypt
Collaborators:
Quesna Central Hospital, Ministry Of Health, Egypt SEDICO pharmaceutical company, Egypt