Overview

Steroids, Thiamine and Ascorbic Acid in Septic Shock

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The objective of this project is to determine if in patients admitted to the hospital with septic shock (population), does treatment with a bundle including hydrocortisone, thiamine, and ascorbic acid improve in-hospital or 28-day mortality (primary outcomes) or surrogate markers of illness severity including: (1) ICU or hospital length-of-stay, (2) duration of invasive mechanical ventilation, (3) duration of vasopressor administration, (4) incidence and severity of ICU delirium, and (5) illness severity (secondary outcomes).
Phase:
Phase 3
Details
Lead Sponsor:
Baqiyatallah Medical Sciences University
Collaborators:
Hamadan University of Medical Science
Tehran University of Medical Sciences
Treatments:
Ascorbic Acid
Thiamine