Overview

Steroids Helping Albuterol Responders Exclusively

Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
0
Participant gender:
All
Summary
The purpose of the study is to determine whether corticosteroids are beneficial to children with bronchiolitis whose breathing gets better after being given a breathing treatment with albuterol.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University Hospitals Cleveland Medical Center
Treatments:
Albuterol
Methylprednisolone
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Criteria
Inclusion Criteria:

- diagnosis of bronchiolitis

- Respiratory Distress Assessment Index score of 4 or more

Exclusion Criteria:

- prior prescription of bronchodilators or inhaled corticosteroids

- birth at <36 weeks gestation

- chronic cardiac disease

- chronic pulmonary disease (including asthma)

- immunodeficiency

- non-topical steroid use in the prior week

- parents that don't understand English

- baseline systolic blood pressure >118 mmHg

- home oxygen use

- evidence of systemic fungal or varicella infection

- bronchodilator use in the prior week

- allergy to albuterol or corticosteroids