Steroid-free and Long-term Calcineurin-free Trial in Islet Cell Transplantation
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
The purposes of this study are:
1. To reverse hyperglycemia and insulin dependency in patients with type 1 diabetes
mellitus through islet transplantation utilizing steroid free, calcineurin-inhibitor
free immunosuppression.
2. To assess the long-term function of successful islet transplants in patients with type 1
diabetes mellitus utilizing islets that have undergone a period of culture.
3. To determine whether the natural history of the microvascular, macrovascular, and
neuropathic complications are altered following the successful transplantation of
islets.