Stem Cells After Peripheral Mobilization and Harvest
Status:
Completed
Trial end date:
2019-09-04
Target enrollment:
Participant gender:
Summary
The proposed study is a controlled laboratory study where stem cell content of bone marrow
aspirate will be compared prior to and following pharmaceutical mobilization. Participants
who meet the inclusion/exclusion criteria will have a bone marrow sample taken from the iliac
crest. The sample will be tested to determine stem cell content and for the presence of
proteins which are of interest in orthopedic treatments. Thirty days following the baseline
bone marrow collection, participants will receive a subcutaneous injection of Filgrastim
daily for four serial days. On the fifth day, a peripheral blood sample will be taken and
processed.