Overview

Stem Cell Transplant in Patients With Severe Sickle Cell Disease

Status:
Recruiting
Trial end date:
2026-02-15
Target enrollment:
Participant gender:
Summary
This is a prospective pilot study of matched-related donor allogeneic stem cell transplantation in adults with severe sickle cell disease using a matched-sibling PBSC graft with a non-myeloablative conditioning regimen (Alemtuzumab).
Phase:
Early Phase 1
Details
Lead Sponsor:
Kathleen Dorritie
Treatments:
Alemtuzumab
Everolimus
Sirolimus