Overview

Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease

Status:
Recruiting
Trial end date:
2026-07-30
Target enrollment:
Participant gender:
Summary
Branch atheromatous disease (BAD) has been reported to contribute to small-vessel occlusion and is associated with a higher possibility of early neurological deterioration (END). Because the pathology of BAD is due to atherosclerosis, the investigators postulate that early intensive medical treatment with dual antiplatelet therapy(DAPT) and high-intensity statin may prevent END and recurrent stroke. The investigators hypothesise that intensive medical therapy can prevent END in BAD using aspirin, clopidogrel and high-intensity statin.
Phase:
Phase 2
Details
Lead Sponsor:
Chang Gung Memorial Hospital
Treatments:
Aspirin
Atorvastatin
Clopidogrel
Rosuvastatin Calcium