Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease
Status:
Not yet recruiting
Trial end date:
2026-01-08
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to test titrated oxygen in prehospital patients with
suspected acute exacerbation of chronic obstructive pulmonary disease (AECOPD) treated with
inhaled bronchodilators. The main question it aims to answer is:
- To determine whether prehospital titrated oxygen strategy in patients with suspected
AECOPD will decrease 30-day mortality compared to patients receiving standard care.
Participants in the intervention will receive titrated oxygen - a mix of supplemental oxygen
and compressed atmospheric air as driver for inhaled bronchodilators to target SpO2 88-92%.
The intervention will be compared to standard treatment, using compressed oxygen (100%) as
driver for inhaled bronchodilators.