Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

• Status: Unknown status
• Trial end date: 1969-12-31

Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Heating mitomycin C to several degrees above normal body temperature and infusing it into the area around the tumor may kill more tumor cells. Giving mitomycin C after surgery may kill any remaining tumor cells. It is not yet known whether standard therapy is more effective with or without surgery followed by mitomycin C.

PURPOSE: This randomized phase III trial is studying standard therapy with or without surgery and mitomycin C in treating patients with advanced limited peritoneal dissemination of colon cancer

• Phase: Phase 3

Details

• Lead Sponsor: Walter Reed Army Medical Center
• Collaborator: National Cancer Institute (NCI)
• Treatments: Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Fluorouracil; Irinotecan; Leucovorin; Levoleucovorin; Mitomycin; Mitomycins; Oxaliplatin