StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial

• Status: NOT_YET_RECRUITING
• Trial end date: 2029-07-01

Summary

Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients. In the SAFEST - RCT, the investigators will assess the impact of starting versus not starting a statin in frail individuals aged 70 and above with a recent ischemic stroke or transient ischemic attack (TIA) on their health-related quality of life and Major Adverse Cardiovascular Events (MACE) free survival during a two-year follow-up period.

• Phase: PHASE4

Details

• Lead Sponsor: Prof. dr. Nathalie van der Velde
• Collaborator: VU University of Amsterdam
• Treatments: Atorvastatin; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Rosuvastatin Calcium; Simvastatin