Overview

Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab

Status:
Completed
Trial end date:
2014-06-13
Target enrollment:
Participant gender:
Summary
This randomized phase II trial studies how well giving spironolactone works in preventing rash in patients with cancer that has spread to other places in the body and are receiving panitumumab and cetuximab. Spironolactone may prevent endothelial growth factor receptor (EGFR) inhibitor-induced skin rash.
Phase:
Phase 2
Details
Lead Sponsor:
Academic and Community Cancer Research United
Collaborator:
National Cancer Institute (NCI)
Treatments:
Cetuximab
Cortisol succinate
Doxycycline
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate
Spironolactone
Sunscreening Agents