Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine Surgery
Status:
Completed
Trial end date:
2018-08-14
Target enrollment:
Participant gender:
Summary
Spine surgery is one of the most common operative procedures in the United States. It is
performed in the prone position (a patient laying on belly). Muscle relaxants are given for
neuromuscular blockade often referred as paralysis for surgical exposure which is maintained
until the patient is returned to the supine position (a patient laying on back) at the end of
surgery. At the end of the surgery the paralysis is reversed with a drug (neostigmine). A new
drug (sugammadex) has the ability to rapidly reverse the paralysis but it is not well
investigated in elderly. This study will investigate speed of recovery and complications of
the two reversal drugs in elderly patients (age ≥ 65 years) undergoing posterior spine
surgery.