Source of Hand Weakness After Stroke

• Status: Withdrawn
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether neural block and neuromuscular electrical stimulation are effective in treating finger impairment due to stroke.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: US Department of Veterans Affairs; VA Office of Research and Development
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• clinical diagnosis of stroke;

• stroke occurred no less than 6 months prior to study;

• must have had only 1 stroke;

• must demonstrate severe hand impairment;

• must have no substantial evidence of motor and sensory deficits in non-paretic limb;

• must have no history or clinical signs of neurologic diseases other than stroke;

• must have no cognitive dysfunction that precludes comprehension of experimental tasks;

• must be able to give informed consent

Exclusion Criteria:

• taking medication that can increase the risk of lidocaine toxicity such as cimetidine (ulcer treatment drug), phenytoin (anticonvulsant drug), nadolol (drug for treatment of headache, hypertension, chest pain);

• taking anticoagulant medication, i.e., aspirin, coumadin;

• has a low platelet count or a bleeding disease