Overview

Sotatercept in Pulmonary Arterial Hypertension

Status:
RECRUITING
Trial end date:
2030-01-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to determine whether sotatercept is effective in improving diffusing capacity in patients with pulmonary arterial hypertension. Participants will be asked to: * Take Sotatercept every 21 days (3 days) * Each participant will be enrolled in the study for 29 Weeks * Visit the clinic 15 times * Have a physical exam * Perform assessments of lung function and exercise tests * Have an ultrasound of their heart * Have blood draws done at regular intervals The main objectives of the study are: Primary objective: To assess whether sotatercept will improve recruitment of diffusing membrane capacity (DM) with exercise. Secondary objective: To identify components of the diffusing capacity that respond to treatment with sotatercept in pulmonary arterial hypertension.
Phase:
PHASE4
Details
Lead Sponsor:
University of Alberta
Collaborators:
Alberta Health services
Merck Canada Inc.
Treatments:
ACE-011