Overview

Sodium-Endothelial Function-CKD Study

Status:
Completed
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
Heart disease and stroke, known as cardiovascular disease, are major causes of death in people with chronic kidney disease. Abnormalities of a metabolic pathway called the "L-arginine-nitric oxide" pathway are thought to be particularly important in these people, and previous research in animals has suggested that sodium (salt) affects part of this metabolic pathway. The purpose of our research is to study the effects of sodium intake on the "L-arginine-nitric oxide" pathway, and on blood vessel function, in patients with kidney disease.
Phase:
N/A
Details
Lead Sponsor:
St George's, University of London
Collaborators:
British Heart Foundation
St. George's Hospital Charitable Foundation