Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Smoking while on nicotine patches will help subjects to reduce their expired carbon monoxide levels from the levels they were before they started using the patch. Subjects will also decrease their daily consumption of cigarettes.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre for Addiction and Mental Health
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• at least 19 years of age

• male or female

• have intention to quit smoking within the next 6 months

• smoke 10 or more cigarettes per day

Exclusion Criteria:

• Pregnant or not using an adequate enough method of birth control to ensure that they are not at risk of becoming pregnant

• breastfeeding

• have any generalized skin disorders

• are in an immediate post-myocardial infarction period or have life-threatening arrhythmias, have severe or worsening angina pectoris or have had a recent cerebral vascular accident

• are using additional nicotine replacement therapies or any other smoking cessation pharmacotherapy

• any clinically significant ECG abnormalities

• any known hypersensitivity to components of the transdermal system