Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches

• Status: Unknown status
• Trial end date: 2010-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To test if smokeless tobacco is more effective than nicotine buccal tablets in smoking cessation compared with a control group with low dose nicotine patches.

Also retreatment will be tested with smokeless tobacco every 6 months in failures for 1½ year. Adherence to the program will be enhanced by assessment of cholesterol, blood pressure, lung function and body weight every 6 months for 2 years.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Gentofte, Copenhagen
• Collaborator: Danish Research Foundation, FSS, Copenhagen, Denmark
• Treatments: Lobeline; Nicotine

Criteria

Inclusion Criteria:

• smokers (>7 cig/day)

• Healthy

• Allowed: treated hypertension, diabetes treated with tablets, increased cholesterol,other "mild" diseases

• mild asthma and COPD,

• Motivated to quit smoking

• Motivated to follow the protocol

• Motivated to use medication in this trial

Exclusion Criteria:

• Severe diseases

• Psychiatric diseases

• Used NRT or Zyban the last 2 weeks

• Stopped smoking >2 days during last 3 months

• More than 6 alcoholic drinks per day

• Smokes other products than cigarettes

• Pregnant of lactating